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There are several matches for 'pseudouridylate synthase'.
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8152 matches
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organism
protein
1)
Escherichia coli K12
psuG - Pseudouridine 5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
[a.k.a. AAC75226.1, b2165, Pseudouridine-5'-phosphate glycosidase,
Pseudouridylate synthase
]
2)
Homo sapiens
PUS7L -
Pseudouridylate
synthase
7 homolog-like protein;
Pseudouridylate
synthase
that catalyzes
pseudouridylation
of RNAs; Belongs to the pseudouridine
synthase
TruD family.
[a.k.a. PUS7L-203, UPI0000037C53, ENST00000549868]
3)
Homo sapiens
PUS7 -
Pseudouridylate
synthase
7 homolog;
Pseudouridylate
synthase
that catalyzes
pseudouridylation
of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating
pseudouridylation
of RNA fragments derived from tRNAs (tRFs):
pseudouridylated
tRFs inhibit translation by targeting the translation initiation complex. Also catalyzes
pseudouridylation
of mRNAs: mediates
pseudouridylation
of mRNAs with the consensus sequence 5'-UGUAG-3'. In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudour [...]
[a.k.a. ENST00000329077, NM_019042.4, OTTHUMG00000157399]
4)
Homo sapiens
TRUB1 - Probable tRNA pseudouridine
synthase
1; Pseudouridine
synthase
that catalyzes
pseudouridylation
of mRNAs. Mediates
pseudouridylation
of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure. Constitutes the major pseudouridine
synthase
acting on mRNAs ; Belongs to the pseudouridine
synthase
TruB family.
[a.k.a. EC 5.4.99.25, CCDS7591.1, ENSP00000358248]
5)
Homo sapiens
PUS10 - Putative tRNA pseudouridine
synthase
Pus10;
Pseudouridylate
synthases
catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death.
[a.k.a. NP_653310.2, NM_144709.3, ENST00000316752]
6)
Homo sapiens
RPUSD4 - Mitochondrial RNA pseudouridine
synthase
RPUSD4; Catalyzes uridine to pseudouridine isomerization (
pseudouridylation
) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translatio [...]
[a.k.a. 5.4.99.-, FLJ14494, OTTHUMG00000165815]
7)
Homo sapiens
RPUSD3 - Mitochondrial mRNA pseudouridine
synthase
RPUSD3; Catalyzes uridine to pseudouridine isomerization (
pseudouridylation
) of specific mitochondrial mRNAs (mt-mRNAs), a post- transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis ; Belongs to the [...]
[a.k.a. 285367, ENST00000473522, 5.4.99.-]
8)
Homo sapiens
PUS1 - tRNA pseudouridine
synthase
A; Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity through
pseudouridylation
of SRA1 RNA; Belongs to the tRNA pseudouridine
synthase
TruA family.
[a.k.a. ENST00000322060, ENST00000538037, HQ205092]
9)
Homo sapiens
TRUB2 - Mitochondrial mRNA pseudouridine
synthase
TRUB2; Minor enzyme contributing to the isomerization of uridine to pseudouridine (
pseudouridylation
) of specific mitochondrial mRNAs (mt- mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.
[a.k.a. ENSP00000361982, 5.4.99.-, A0A024R886]
10)
Mus musculus
Pus7l -
Pseudouridylate
synthase
7 homolog-like protein;
Pseudouridylate
synthase
that catalyzes
pseudouridylation
of RNAs; Belongs to the pseudouridine
synthase
TruD family.
[a.k.a. ENSMUSG00000033356, Q8CE46, ENSMUST00000147832.1]
11)
Mus musculus
Pus7 -
Pseudouridylate
synthase
7 homolog;
Pseudouridylate
synthase
that catalyzes
pseudouridylation
of RNAs. Acts as a regulator of protein synthesis in embryonic stem cells by mediating
pseudouridylation
of RNA fragments derived from tRNAs (tRFs):
pseudouridylated
tRFs inhibit translation by targeting the translation initiation complex. Also catalyzes
pseudouridylation
of mRNAs: mediates
pseudouridylation
of mRNAs with the consensus sequence 5'-UGUAG-3'. In addition to mRNAs and tRNAs, binds other types of RNAs, such as snRNAs, Y RNAs and vault RNAs, suggesting that it can catalyze pseudour [...]
[a.k.a. Pus7-201, ENSMUST00000151449, CCDS80219.1]
12)
Mus musculus
Trub1 - Probable tRNA pseudouridine
synthase
1; Pseudouridine
synthase
that catalyzes
pseudouridylation
of mRNAs. Mediates
pseudouridylation
of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure. Constitutes the major pseudouridine
synthase
acting on mRNAs; Belongs to the pseudouridine
synthase
TruB family.
[a.k.a. Q8C0D0, mmu:72133, EC 5.4.99.25]
13)
Mus musculus
Pus10 - Putative tRNA pseudouridine
synthase
Pus10;
Pseudouridylate
synthases
catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. PUS10 catalyzes the formation of the universal psi55 in the GC loop of transfer RNAs (Probable). Modulator of TRAIL-induced cell death via activation of procaspase 8 and BID cleavage. Required for the progression of the apoptotic signal through intrinsic mitochondrial cell death (By similarity).
[a.k.a. EC 5.4.99.25, tRNA-uridine isomerase, XM_006514863.2]
14)
Mus musculus
Rpusd2 - RNA
pseudouridylate
synthase
domain-containing protein 2; Belongs to the pseudouridine
synthase
RluA family.
[a.k.a. RNA pseudouridylate synthase domain containing 2, AAI17829.1, ENSMUST00000028796.1]
15)
Mus musculus
Rpusd1 - RNA
pseudouridylate
synthase
domain-containing protein 1; Belongs to the pseudouridine
synthase
RluA family.
[a.k.a. CH466606, 2310051D06Rik, Q8VCZ8]
16)
Mus musculus
Rpusd4 - Mitochondrial RNA pseudouridine
synthase
Rpusd4; Catalyzes uridine to pseudouridine isomerization (
pseudouridylation
) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt- rRNA, controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation.
[a.k.a. 5.4.99.-, ENSMUST00000034543, ENSMUST00000034543.4]
17)
Mus musculus
Rpusd3 - Mitochondrial mRNA pseudouridine
synthase
Rpusd3; Catalyzes uridine to pseudouridine isomerization (
pseudouridylation
) of specific mitochondrial mRNAs (mt-mRNAs), a post- transcriptional modification necessary for their translation. Acts at position 390 in COXI mt-mRNA and at position 697-699 in mitochondrial COXIII mt-mRNA. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and may play a role in mitochondrial ribosome biogenesis.
[a.k.a. 5.4.99.-, NM_001346511, NM_001346511.1]
18)
Mus musculus
Trub2 - Mitochondrial mRNA pseudouridine
synthase
Trub2; Minor enzyme contributing to the isomerization of uridine to pseudouridine (
pseudouridylation
) of specific mitochondrial mRNAs (mt- mRNAs) such as COXI and COXIII mt-mRNAs. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.
[a.k.a. 5.4.99.-, ENSMUST00000156846, Mitochondrial mRNA pseudouridine synthase Trub2]
19)
Mus musculus
Pus1 - tRNA pseudouridine
synthase
A; Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA. Involved in regulation of nuclear receptor activity possibly through
pseudouridylation
of SRA1 RNA. Isoforms 3 and 4 do not form pseudouridine when expressed in vitro.
[a.k.a. ENSMUSG00000029507, uc008yrn.1, Q791J1]
20)
Drosophila melanogaster
Nop60B - H/ACA ribonucleoprotein complex subunit 4; Plays a central role in ribosomal RNA processing. Probable catalytic subunit of H/ACA small nucleolar ribonucleoprotein (H/ACA snoRNP) complex, which catalyzes
pseudouridylation
of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ('psi') residues may serve to stabilize the conformation of rRNAs. Required for maintenance of the germline stem cell lineage during spermatogenesis; Belongs to the pseudouridine
synthase
TruB family.
[a.k.a. FBgn0259937, Nop60B-PF, Nop60B-PC]
8152 matches
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